Hemoglobin San Diego (β109 (G11) Val→Met) CRYSTAL STRUCTURE OF THE DEOXY FORM

Hemoglobinopathic erythrocytosis due to a new electrophoretically silent variant, hemoglobin San Diego (beta109 (G11)val--met).

Examination of 13 members of a Filipino family revealed that 6 had erythrocytosis inherited as a simple autosomal dominant trait. Application of several electrophoretic and chromatographic tests failed to reveal the presence of an abnormal hemoglobin in hemolysates from affected individuals. However, measurements of oxygen dissociation curves using whole bloods, dialyzed hemolysates, and 2,3-di...

First Observation of Hemoglobin San Diego, a High Oxygen Affinity Hemoglobin Variant, in Turkey

Figure 1. A) Pedigree of the family with erythrocytosis and hemoglobin (Hb) San Diego, illustrating dominant mode of inheritance of erythrocytosis. The propositus is indicated with an arrow; B) high-performance liquid chromatography (premier Hb9210 resolution) showing the presence of Hb San Diego. Ebru Yılmaz Keskin1, Ali Fettah2, Ana Catarina Oliveira3, Şule Toprak2, Andreia Lopes3, Celeste Be...

UC San Diego UC

SSC San Diego TR1832

Approved for public release; distribution is unlimited. ACKNOWLEDGMENTS These studies were conducted with the assistance and cooperation of the Fifth Marine Regiment, Camp Pendleton, CA. We would like to thank Colonel Brooks, Commanding Officer of Fifth Marines, and Major Turner (his S-3), for their unselfish dedication of time and effort in facilitating access to the officers and staff noncomm...

Paramedics– San Diego Experience

Background. Prehospital personnel in Emergency Medical Service (EMS) systems have varying levels of accuracy in stroke recognition. Identifying the accuracy of emergency medical dispatcher using Medical Priority Dispatch Systems (MPDS) stroke protocol and paramedics may help understand the accuracy of stroke recognition in about 3000 emergency medical dispatch systems and prehospital systems wo...